Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine.

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Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine.

Comment Both these patients were positive for HIV antibody and had a clinical and radiological presentation suggestive of P carinni pneumonia that responded to treatment; thus the criteria fbr a diagnosis of AIDS were satisfied. ' In case 2 the diagnosis was complicated by the previous amiodarone treatment, though pneumonitis induced by amiodarone is unusual at a daily dosage less than 400 mg.2...

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Flunarizine and cinnarizine-induced parkinsonism: a historical and clinical analysis.

BACKGROUND Drug-Induced Parkinsonism (DIP) represents the second leading cause of Parkinsonism (PK) in several countries. Flunarizine and cinnarizine are some of the most common drugs that cause DIP. This paper reviews the first description of Flunarizine and Cinnarizine-Induced Parkinsonism (FCIP), as well as the subsequent literature, emphasizing epidemiological, clinical and diagnostic aspec...

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Flunarizine and cinnarizine-induced parkinsonism: 25 years of de Melo-Souza's syndrome.

Drug-induced Parkinsonism (DIP) is the second most common cause of parkinsonism (PK). Flunarizine and cinnarizine induced parkinsonism (FCIP) is one of the most frequent forms and is commonly found in elderly female patients manifesting symmetrical motor symptoms with resting and/or postural tremor, often associated with depression, and occasionally acathisia and dyskinesia . FCIP was first des...

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Parkinsonism and other movement disorders in outpatients in chronic use of cinnarizine and flunarizine.

The purpose of this study is to determine the prevalence and the patterns of movement disorders (MD) in outpatients submitted to the chronic use of cinnarizine (cz) or flunarizine (fz), and to establish the main risk factors for MD development. Over a period of 3 months, data were collected from outpatients who were chronic users of cz or fz in a municipal health institute. A total of 26 outpat...

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Minocycline Mitigation of Tremor Syndrome and Defect of Cognitive and Balance Induced by Harmaline

Introduction: Minocycline has anti-inflammatory, anti-apoptotic, and anti-oxidant effects. Preclinical data suggest that minocycline could be beneficial for treating common neurological disorders, including Parkinson disease and multiple sclerosis. Methods: In this study, the effects of minocycline on harmaline-induced motor and cognitive impairments were studied in male Wistar rats. The rats ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1988

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.297.6650.722